RCN1 protein (His tag) (80R-1434)

Purified recombinant Human RCN1 protein

Synonyms Reticulocalbin-1 protein, Reticulocalbin 1 protein, RCN1, RCAL protein, PIG20 protein, RCN-1 protein, RCN-1, Reticulocalbin1, RCN 1, RCN 1 protein, RCN protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Specifications

Residues 30-331 amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSELEK PTVRKERVVR PDSELGERPP EDNQSFQYDH EAFLGKEDSK TFDQLTPDES KERLGKIVDR IDNDGDGFVT TEELKTWIKR VQKRYIFDNV AKVWKDYDRD KDDKISWEEY KQATYGYYLG NPAEFHDSSD HHTFKKMLPR DERRFKAADL NGDLTATREE FTAFLHPEEF EHMKEIVVLE TLEDIDKNGD GFVDQDEYIA DMFSHEENGP EPDWVLSERE QFNEFRDLNK DGKLDKDEIR HWILPQDYDH AQAEARHLVY ESDKNKDEKL TKEEILENWN MFVGSQATNY GEDLTKNHDE L
Expression System E.coli
Purity > 80% pure
Molecular Weight 40.4 kDa (341aa) confirmed by MALDI-TOF (Real molecular weight on SDS-PAGE will be shift up)
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol, 1mM DTT and 100mM NaCl.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Reticulocalbin 1(RCN1) is a calcium-binding protein. It binds calcium and may regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane. Recombinant human RCN1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

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Availability: In stock

Price: $255.00
Size: 50 ug
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