Reticulon 1A antibody (10R-8104)

Mouse monoclonal Reticulon 1A antibody

Synonyms Monoclonal Reticulon 1A antibody, Anti-Reticulon 1A antibody, MGC133250 antibody, Neuroendocrine specific protein antibody, NSP antibody, Reticulon 1 antibody, Reticulon1 antibody, Reticulon1A antibody, RTN 1 antibody, RTN1 antibody, RTN1 protein antibody,NSPA antibody, NSP-A antibody, Reticulon 1A
Specificity Recognizes the 135 kD Reticulon-1A protein in immunoblots of NCI-H82 and other SCLC cell lines, and stains normal and pathological neural and neuroendocrine tissues
Cross Reactivity Hamster, Human, Mouse, Rat
Applications FC, IHC, IHC-F, IHC-P, WB
Immunogen Reticulon 1A antibody was raised in Mouse using a partially purified bacterially expressed Reticulon-1A (NSP-A) hybrid protein (betaGAL-NSP-A 6-776) as the immunogen.

Specifications

Host Mouse
Clone MON161
Isotype IgG1
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations IHC: 1:50-1:100, WB: 1:50-1:500

General Information

Biological Significance Reticulon-1A is a protein with a molecular weight (MW) of about 135 kDa, which occurs in various isoforms presumably depending on the degree of phosphorylation of serine residues. In lung cancer diagnosis Reticulon-1A appeared to be a reliable marker for the detection of neuroendocrine differentiation, since most of the small cell lung carcinoma (SCLC) and carcinoid tumors showed expression of Reticulon-1A. Reticulon-1B is a phosphoprotein with a MW of 45 kDa and is restricted to the lung cancer cell line NCI-H82.

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Availability: In stock

Price: $405.00
Size: 100 ug
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