Reticulon 1A/B antibody (10R-8106)

Mouse monoclonal Reticulon 1A/B antibody

Synonyms Monoclonal Reticulon 1A/B antibody, Anti-Reticulon-1A/B antibody, MGC133250 antibody, Neuroendocrine specific protein antibody, NSP antibody, Reticulon 1 antibody, Reticulon1 antibody, Reticulon1A antibody, RTN 1 antibody, RTN1 antibody, RTN1 protein antibody,NSPA antibody, NSP-A antibody, Reticulon1AB antibody, Reticulon 1 AB antibody, Reticulon 1A/B
Specificity Recognizes an epitope located within the region of amino acids 421-589 of the neuro-endocrine specific protein Reticulon-1A (NSP-A), which is also present in the N-terminal part of Reticulon-1B (NSP-B)
Cross Reactivity Human, Monkey, Rabbit
Applications FC, IHC, IHC-F, IHC-P, WB
Immunogen Reticulon 1A/B antibody was raised in Mouse using the small cell lung cancer cell line NCI-H82 as the immunogen.

Specifications

Host Mouse
Clone RNL-2
Isotype IgG1
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations IHC: 1:25-1:200, WB: 1:100-1:1000

General Information

Biological Significance Recently, a novel gene family has been identified and characterized, designated the Reticulons because the proteins encoded by these genes are anchored to the membranes of the endoplasmic reticulum. Reticulon-1 was formerly designated NSP for Neuroendocrine-Specific-Protein, because it is specifically expressed in neural and neuroendocrine tissues. The NSP-gene has been mapped by fluorescence in situ hybridization to human chromosome 14q21-q22. The NSP-gene encodes three overlapping proteins, i.e. Reticulon-1A (NSP-A), Reticulon-1B (NSP-B), and Reticulon-1C (NSP-C). These proteins were found to be anchored to membranes of the endoplasmic reticulum through their common carboxy-terminal regions.

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Availability: In stock

Price: $385.00
Size: 100 ug
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