REXO2 protein (His tag) (80R-2857)
Purified recombinant REXO2 protein (His tag)
|Synonyms||REXO2, REXO 2, REXO-2, REXO2, REXO 2 protein, REXO-2 protein, Oligoribonuclease protein, mitochondrial protein, REX2 protein, RNA exonuclease 2 homolog (S. cerevisiae) protein, CGI-114 protein, REX2 protein, RFN protein, SFN protein|
SDS-PAGE analysis of REXO2 protein (His tag) (80R-2857)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||26-237 aa: MGSSHHHHHH SSGLVPRGSH MGSVREGGAA MAAGESMAQR MVWVDLEMTG LDIEKDQIIE MACLITDSDL NILAEGPNLI IKQPDELLDS MSDWCKEHHG KSGLTKAVKE STITLQQAEY EFLSFVRQQT PPGLCPLAGN SVHEDKKFLD KYMPQFMKHL HYRIIDVSTV KELCRRWYPE EYEFAPKKAA SHRALDDISE SIKELQFYRN NIFKKKIDEK KRKIIENGEN EKTVS|
|Purity||> 90% pure|
|Molecular Weight||26.8 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol|
Storage & Safety
|Storage||Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.|
|Biological Significance||REXO2 is a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process. Recombinant human REXO2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
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