RGN protein (His tag) (80R-1946)

Recombinant human RGN protein

Synonyms RC protein, SMP30 protein, Regucalcin protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of RGN protein (His tag) (80R-1946)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-299 amino acids: MGSSHHHHHH SSGLVPRGSH MSSIKIECVL PENCRCGESP VWEEVSNSLL FVDIPAKKVC RWDSFTKQVQ RVTMDAPVSS VALRQSGGYV ATIGTKFCAL NWKEQSAVVL ATVDNDKKNN RFNDGKVDPA GRYFAGTMAE ETAPAVLERH QGALYSLFPD HHVKKYFDQV DISNGLDWSL DHKIFYYIDS LSYSVDAFDY DLQTGQISNR RSVYKLEKEE QIPDGMCIDA EGKLWVACYN GGRVIRLDPV TGKRLQTVKL PVDKTTSCCF GGKNYSEMYV TCARDGMDPE GLLRQPEAGG IFKITGLGVK GIAPYSYAG
Expression System E.coli
Purity > 85% pure
Molecular Weight 35.4 kDa (319aa)
Tag/Conjugate His tag
Form & Buffer Liquid. In 20mM Tris-HCl, pH8.0, 2M Urea, 20%Glycerol
Concentration 0.5 mg/ml

Usage & Assay Information

Usage Recommendations RGN protein (His tag) has been used in SDS PAGE, and may be suitable for use in other assays, to be determined by the end user.

Storage & Safety

Storage Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.

General Information

Biological Significance RGN (Regucalcin) belongs to the SMP-30/CGR1 family. This protein is Ca (2+)-binding protein that does not contain EF-hand motif of Ca (2+)-binding domain. RGN plays a pivotal role in the keep of intracellular Ca2+ homeostasis due to activating Ca2+ pump enzymes in the plasma membrane (basolateral membrane), microsomes (endoplasmic reticulum) and mitochondria of many cells. Also, it plays a multifunctional role in the regulation of cell functions in liver, kidney cortex, heart and brain and a suppressor protein for cell signaling systems in many cell types.

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Images

  • Coomassie Blue stained SDS-PAGE of RGN protein (His tag) (80R-1946) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $270.00
Size: 100 ug
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