Rifabutin (USP grade powder) (51R-U603800)
Rifabutin (USP grade powder) chemical reference substance
|Form & Buffer||Supplied as a powder.|
|Biological Significance||Rifabutin (Rfb) is a bactericidal antibiotic drug primarily used in the treatment of tuberculosis. The drug is a semi-synthetic derivative of rifamycin S. Its effect is based on blocking the DNA-dependent RNA-polymerase of the bacteria. It is effective against Gram-positive and some Gram-negative bacteria, but also against the highly resistant Mycobacteria, e.g. Mycobacterium tuberculosis, M. leprae and M. avium intracellulare.|
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