RPTP rho antibody (10R-8624)

Mouse monoclonal RPTP rho antibody

Synonyms Monoclonal RPTP rho antibody, Anti-RPTP rho antibody, PTPRT antibody, protein tyrosine phosphatase antibody, receptor type antibody, T antibody, BOS_13082 antibody, mRPTPrho antibody, ptprt-a antibody, receptor protein tyrosine phosphatase antibody, receptor protein tyrosine phosphatase rho antibody, receptor protein tyrosine phosphatase-rho antibody, receptor-type tyrosine-protein phosphatase rho antibody, receptor-type tyrosine-protein phosphatase T antibody, RP23-466K24.1 antibody, RP5-1121H13.2 antibody, RPTPmam4 antibody, RPTP-rfo antibody, rptprho antibody, RPTP-rho antibody, R-PTP-T antibody
Cross Reactivity Human
Applications IP, WB
Immunogen RPTP rho antibody was raised in Mouse using a recombinant human protein purified from E.coli as the immunogen

Images

Western Blot analysis using RPTP rho antibody (10R-8624)

Specifications

Host Mouse
Clone T20-AF3C7
Isotype IgG1 kappa
Method of Purification RPTP rho antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:5000, IP: 2 ul

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance RPTP rho is a transmembrane protein that is highly expressed in the developing and adult central nervous system. It is a member of the RPTP R2B subfamily, which includes PTPK, PTPµ and PCP-2. The R2B phosphatases are known to interact with members of the cadherin/catenin complex. These four RPTPs share the same domain structure: an extracelluar domain, a juxtamembrane region, and two phosphatase domains. The extracellular domain of PTPR mediates cell-cell aggregation and that mutational inactivation of this phosphatase could promote tumor migration and metastasis. PTPRT is the most frequently mutated PTP in human cancers. STAT3 is a substrate of PTPRT.

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Images

  • Western Blot analysis using RPTP rho antibody (10R-8624) |

Availability: In stock

Price: $295.00
Size: 100 ul
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