RRAS protein (His tag) (80R-1299)
Purified recombinant Human RRAS protein
|Synonyms||Ras like protein TC21 protein, TC 21 protein, Oncogene TC21 protein, TC21 protein, Ras-related protein R-Ras C86394 protein, Oncogene RRAS2 protein, Related RAS viral (r ras) oncogene homolog 2 protein, Related RAS viral oncogene homolog 2 protein, Teratocarcinoma oncogene TC21., Ras related protein R Ras2 protein, Teratocarcinoma oncogene protein, RRAS 2 protein, protein|
Coomassie Blue stained SDS-PAGE of RRAS protein (His tag) (80R-1299)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-215 amino acids: MGSSHHHHHH SSGLVPRGSH MSSGAASGTG RGRPRGGGPG PGDPPPSETH KLVVVGGGGV GKSALTIQFI QSYFVSDYDP TIEDSYTKIC SVDGIPARLD ILDTAGQEEF GAMREQYMRA GHGFLLVFAI NDRQSFNEVG KLFTQILRVK DRDDFPVVLV GNKADLESQR QVPRSEASAF GASHHVAYFE ASAKLRLNVD EAFEQLVRAV RKYQEQELPP SPPSAPRKKG GGCPC|
|Purity||> 85% pure|
|Molecular Weight||25.3 kDa (235aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol and 0.1M NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||RRAS, also known as ras-related protein R-Ras, belongs to the Ras family which functions in signal transduction pathways. This protein has been shown to interact with RASSF5, NCK1, Bcl-2, ARAF and RALGDS. RRAS can bind GTP and GDP, and it has intrinsic GTPase activity. It also regulates the organization of the actin cytoskeleton. Recombinant RRAS protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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