RTN3 antibody (10R-1829)
Mouse monoclonal RTN3 antibody
|Synonyms||Monoclonal RTN3 antibody, Anti-RTN3 antibody, RTN-3 antibody, RTN 3, RTN 3 antibody, Reticulon 3 antibody, RTN-3, RTN3|
|Immunogen||RTN3 antibody was raised in Mouse using a purified recombinant fragment of RTN3 expressed in E. coli as the immunogen.|
Immunofluorescent staining using (RTN3 antibody)
Confocal immunofluorescence analysis of Hela (A), A431 (B) and THP-1 (C) cells using RTN3 antibody (green). Blue: DRAQ5 fluorescent DNA dye.
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, IF: 1:200-1:1000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||RTN3 may be involved in membrane trafficking in the early secretory pathway. It is thought to inhibit BACE1 activity and amyloid precursor protein processing. It may also induce caspase-8 cascade and apoptosis. RTN3 may favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis.|
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