RTN3 antibody (10R-1829)

Mouse monoclonal RTN3 antibody

Synonyms Monoclonal RTN3 antibody, Anti-RTN3 antibody, RTN-3 antibody, RTN 3, RTN 3 antibody, Reticulon 3 antibody, RTN-3, RTN3
Cross Reactivity Human
Applications ELISA, IF
Immunogen RTN3 antibody was raised in Mouse using a purified recombinant fragment of RTN3 expressed in E. coli as the immunogen.

Images

Immunofluorescent staining using (RTN3 antibody)

Confocal immunofluorescence analysis of Hela (A), A431 (B) and THP-1 (C) cells using RTN3 antibody (green). Blue: DRAQ5 fluorescent DNA dye.

Specifications

Host Mouse
Clone 1E11
Isotype IgG2a
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IF: 1:200-1:1000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance RTN3 may be involved in membrane trafficking in the early secretory pathway. It is thought to inhibit BACE1 activity and amyloid precursor protein processing. It may also induce caspase-8 cascade and apoptosis. RTN3 may favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis.

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Images

  • Immunofluorescent staining using  (RTN3 antibody) | Confocal immunofluorescence analysis of Hela (A), A431 (B) and THP-1 (C) cells using RTN3 antibody (green). Blue: DRAQ5 fluorescent DNA dye.

Availability: In stock

Price: $345.00
Size: 100 ul
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