RUNX1 antibody (10R-1279)

Mouse monoclonal RUNX1 antibody

Synonyms Monoclonal RUNX1 antibody, Anti-RUNX1 antibody, RUNX 1 antibody, AML1 antibody, AMLCR1 antibody, RUNX-1, CBFA2 antibody, RUNX1, AML1-EVI-1 antibody, Runt-related transcription factor 1 antibody, RUNX 1, PEBP2aB antibody, EVI-1 antibody, RUNX-1 antibody
Specificity Human RUNX1
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen RUNX1 antibody was raised in mouse using recombinant Human Runt-Related Transcription Factor 1 (Acute Myeloid Leukemia 1; Aml1 Oncogene) (Runx1)

Images

Western Blot analysis of immunized recombinant protein using RUNX1 antibody (10R-1279)

Specifications

Host Mouse
Clone RUNXA3B6
Isotype IgG1
Method of Purification RUNX1 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer RUNX1 antibody in PBS (3.0 mM KCl,1.5 mM KH2PO4 , 140 mM NaCl, 8.0 mM Na2HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance RUNX1 is a eukaryotic gene and the protein encoded by this gene is a transcription factor associated with M2 AML, a type of leukemia. It belongs to the Runt-related transcription factor (RUNX) family of genes which are also called core binding factor-alpha (CBFalpha). RUNX proteins form a heterodimeric complex with CBFbeta which confers increased DNA binding and stability to the complex.

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Images

  • Western Blot analysis of immunized recombinant protein using RUNX1 antibody (10R-1279)

Availability: In stock

Price: $190.00
Size: 50 ug
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