S100A6 protein (His tag) (80R-1848)

Purified recombinant S100A6 protein

Synonyms S100A6, S100 calcium binding protein A6 (calcyclin) protein, 5B10 protein, 2A9 protein, PRA protein, CALCYCLIN protein, SA6 100 protein, SA6-100 protein, Cacy protein, SA6 100, SA6-100
Species Mouse
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of S100A6 protein (His tag) (80R-1848)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-89 amino acids: MGSSHHHHHH SSGLVPRGSH MACPLDQAIG LLVAIFHKYS GKEGDKHTLS KKELKELIQK ELTIGSKLQD AEIARLMDDL DRNKDQEVNF QEYVAFLGAL ALIYNEALK
Expression System E.coli
Purity > 95% pure
Molecular Weight 12.2 kDa (109aa), confirmed by MALDI-TOF
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT, 30% glycerol and 100mM NaCl.
Concentration 0.5 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance S100 calcium binding protein A6 (S100A6) belongs to the S100 family. S100 family contains 2 EF-hand calcium-binding motifs. S100 proteins regulate a number of cellular processes such as cell cycle progressions and differentiation. S100A6 plays a role in the reorganization of the actin cytoskeleton and in cell mobility. This is a specific target of S-100B protein in vivo. The binding of S100A6 to S100B is stabilized by S100B-bound calcium and zinc. It associates with both Annexin XI and CacyBP (Calcyclin-binding protein). It functions to activate several processes along the calcium signal transduction pathway including the regulation of cell growth, proliferation, secretion and exocytosis. Recombinant mouse S100A6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of S100A6 protein (His tag) (80R-1848) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $255.00
Size: 100 ug
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