S100A7 protein (His tag) (80R-1749)
Purified recombinant Human S100A7 protein
|Synonyms||S100A7, SA7-100, SA7-100 protein, S100 calcium binding protein A7 protein, S100A7c protein, SA7 100, SA7 100 protein|
Coomassie Blue stained SDS-PAGE of S100A7 protein (His tag) (80R-1749)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-101 amino acids: MGSSHHHHHH SSGLVPRGSH MSNTQAERSI IGMIDMFHKY TRRDDKIDKP SLLTMMKENFPNFLSACDKK GTNYLADVFE KKDKNEDKKI DFSEFLSLLG DIATDYHKQS HGAAPCSGGS Q|
|Purity||> 95% pure|
|Molecular Weight||13.6 kDa (121aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 30% glycerol, 0.1M NaCl and 1mM DTT.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||S100A7, also known as Psoriasin, belongs to the S-100 family of calcium binding proteins and is secreted via a non-classical secretory pathway into the cytoplasm. It is thought to function in the regulation of many cellular processes, including the cell cycle, cell progression and cellular differentiation. It contains two EF-hand domains and is highly upregulated in psoriatic epidermis, as well as in bladder squamous cell carcinoma and breast cancer tissue, suggesting a possible role in carcinogenesis. Recombinant human S100A7 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.|
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