SDCBP protein (His tag) (80R-1570)
Purified recombinant Human SDCBP protein
|Synonyms||Syntenin-1 protein, MDA-9 protein, TACIP18, ST1 protein, SYCL protein|
Coomassie Blue stained SDS-PAGE of SDCBP protein (His tag) (80R-1570)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-298 amino acids: MGSSHHHHHH SSGLVPRGSH MSLYPSLEDL KVDKVIQAQT AFSANPANPA ILSEASAPIP HDGNLYPRLY PELSQYMGLS LNEEEIRANV AVVSGAPLQG QLVARPSSIN YMVAPVTGND VGIRRAEIKQ GIREVILCKD QDGKIGLRLK SIDNGIFVQL VQANSPASLV GLRFGDQVLQ INGENCAGWS SDKAHKVLKQ AFGEKITMTI RDRPFERTIT MHKDSTGHVG FIFKNGKITS IVKDSSAARN GLLTEHNICE INGQNVIGLK DSQIADILST SGTVVTITIM PAFIFEHIIK RMAPSIMKSL MDHTIPEV|
|Purity||> 90% pure|
|Molecular Weight||34.6 kDa(318aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl Buffer, pH 8.0, containing 100mM NaCl and 40% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||SDCBP, also known as Syntenin1, is a multifunctional intracellular adapter protein. This protein contains tandemly repeated PDZ domains that react with the FYA (phe-tyr-ala) carboxyterminal amino acid sequence of the syndecans. It is involved in organization of protein complexes in the plasma membranes, regulation of B-cell development, activation of transcription factors, intracellular trafficking and cell-surface targeting, synaptic transmission, and axonal outgrowth. Recombinant human SDCBP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.|
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