Immunoglobulin E (IgE) antibodies are present in minute amounts compared to other immunoglobulins in the body but play a major role in allergic diseases. IgE is found only in mammals and its main defensive function is immunity to parasites such as parasitic worms. Asthma, allergic rhinitis, food allergy, urticaria, dermatitis and allergic reactions to certain drugs, bee stings etc are all a result of IgE mediated hypersensitivity. IgE mediates these allergic responses are a result of binding to Fc receptors found on the surface of mast cells and basophils.
Allergies and allergy treatments are a lucrative global market, targeting the IgE, the IgE synthesis pathway, and the IgE-mediated allergic/inflammatory pathways are an effective way for pharmaceutical researchers to develop new drug targets and treatments for conditions such as asthma and food allergies.
Fitzgerald Industries offers a wide range of IgE antibodies of the highest quality for research and diagnostic use. Our IgE antibodies are raised in most commonly used host animals and available conjugated to most commonly utilized conjugate tags.
Popular IgE antibodies in our catalog include:
Mouse anti Rat IgE a monoclonal rat IgE antibody (clone MARE-1) which is suitable for ELISA, IHC and Western blotting. This IgG1 kappa isotype is supplied in a lyophilized format.
Our purified Mouse anti Human IgE is a very popular human IgG antibody. It is a monoclonal which is highly specific for human IgE and is available in large quantities.
Human IgE antibody is for use in ELISA assays, immunofluorescence, immunohistochemistry and radioimmunoassays.
This polyclonal Goat anti Human IgE is affinity purified and can be applied to a wide range of assays including ELISA, ICC and IHC, and is supplied with excellent usage instructions.
Rat anti Mouse IgE (clone LO-ME-3) is supplied in PBS and can be used in ELISA.
Check out our website for more IgE secondary antibodies....