Serum amyloid P component antibody (10R-8443)

Mouse monoclonal Serum amyloid P component antibody

Synonyms Monoclonal Serum amyloid P component antibody, Anti-Serum amyloid P component antibody, APCS antibody, amyloid P component antibody, serum antibody, 9.5S alpha-1-glycoprotein antibody, amyloid P component serum antibody, amyloid P component antibody, serum protein antibody, APCS amyloid P-component serum protein antibody, BOS_2647 antibody, C-reactive protein antibody, pentaxin-related antibody, pentraxin antibody, ptx2 antibody, Sap antibody, serum amyloid P component antibody, serum amyloid P-component antibody
Cross Reactivity Human
Applications ELISA, IP, WB
Immunogen Serum amyloid P component antibody was raised in Mouse using a protein purified from Human plasma as the immunogen

Images

Western Blot analysis using Serum amyloid P component antibody (10R-8443)

Specifications

Host Mouse
Clone 6E6
Isotype IgG1 kappa
Method of Purification Serum amyloid P component antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000, IP: 1 ul

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Serum amyloid P component (SAP) is a normal plasma protein and a universal non-fibrillar constituent of amyloid deposits. SAP is a member of the pentraxin protein family which includes C-reactive protein. Human SAP is secreted and catabolized only by hepatocytes, and consists of five identical non-covalently associated subunits, each with a molecular mass of 25 kDa, which are non-covalently associated in a pentameric disc-like ring. SAP is a calcium-dependent ligand binding protein, which binds to DNA and chromatin, and to all known types of amyloid fibrils accounting for its specific accumulation in amyloid deposits. Serum amyloid P component scintigraphy is a non-invasive and quantitative method for imaging amyloid deposits, which produces diagnostic images in most patients with systemic amyloidosis, and can be used repeatedly to monitor the course of the disease.

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Images

  • Western Blot analysis using Serum amyloid P component antibody (10R-8443) |

Availability: In stock

Price: $295.00
Size: 100 ul
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