SHBG protein (30C-CP2020P)

Purified native Human SHBG protein

Synonyms Sex Hormone Binding Globulin protein
Species Human
Protein Type Native
Applications User optimized

Specifications

Source Human plasma
Purity > 50% pure
Form & Buffer Lyophlized from 5mM TRIS-HCl, pH 7.6, with 1mM CaCl2.

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles

General Information

Biological Significance SHBG transports the sex steroids testosterone, DHT and estradiol in the blood. Serum levels are increased during pregnancy, in women taking estrogens, and in men over the age of 50. Levels are reduced after menopause and in response to treatment with androgens or corticosteroids. Diagnostic uses include polycystic ovary disease and tests for liver and thyroid function.

References
Add a Paper

Hagen Hauptmanna, Jochen Metzgerb, Andreas Schnitzbauerb, Claude Y Cuilleronc, Elisabeth Mappusc, Peter B Luppa

Syntheses and ligand-binding studies of 1A- and 17A-aminoalkyl dihydrotestosterone derivatives to human sex hormone-binding globulin

Steroids

Volume: 68 Issue: 7-8 Page: 629-639 DOI: 10.1016/S0039-128X(03)00092-8

Huika Li, Thy Pham, Brett C. McWhinney, Jacobus P. Ungerer, Carel J. Pretorius, Derek J. Richard, Robin H.Mortimer, Michael C. d’Emden, and Kerry Richard

Sex Hormone Binding Globulin Modifies Testosterone Action and Metabolism in Prostate Cancer Cells

International Journal of Endocrinology

Volume: 2016 DOI: 10.1155/2016/6437585

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Availability: In stock

Price: $2,727.00
Size: 10 mg
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