SHP1 antibody (10R-8496)

Mouse monoclonal SHP1 antibody

Synonyms Monoclonal SHP1 antibody, Anti-SHP1 antibody, PTPN6 antibody, protein tyrosine phosphatase antibody, non-receptor type 6 antibody, 70Z-SHP antibody, BOS_5967 antibody, dentatorubro-pallidoluysian atrophy protein antibody, DRPLA antibody, fj22f05 antibody, hcp antibody, HCPH antibody, hematopoietic cell phosphatase antibody, hematopoietic cell protein-tyrosine phosphatase antibody, hemopoietic cell phosphatase antibody, hptp1c antibody, me antibody, motheaten antibody, non-receptor type protein tyrosine phosphatase SHP1 antibody, protein-tyrosine phosphatase 1C antibody, protein-tyrosine phosphatase SHP-1 antibody, ptp-1c antibody, Ptp1C antibody, Ptph6 antibody, PTPTY-42 antibody, RCJMB04_15p22 antibody, SH2 phosphatase 1 antibody, shp1 antibody, SHP-1 antibody, SHP-1L antibody, sh-ptp1 antibody, src homology 2 domain-containing phosphatase-1 antibody, tyrosine-protein phosphatase non-receptor type 6 antibody, tyrosine protein phosphatase non-receptor type 6-like protein antibody
Cross Reactivity Human
Applications ELISA, WB
Immunogen SHP1 antibody was raised in Mouse using a recombinant human protein purified from E.coli(His/ABD-SHP1) as the immunogen

Images

Western Blot analysis using SHP1 antibody (10R-8496)

Specifications

Host Mouse
Clone 10F5
Isotype IgG1 kappa
Method of Purification SHP1 antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1: 2000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance SHP1 is implicated in signaling from receptor tyrosine kinases (RTKs), cytokine receptors, chemokine receptors and integrins. SHP1-deficient bone marrow macrophages are hyper-adherent to beta1- and beta2-integrin ligands. Decreased SHP1 level causes abnormal T-lymphocyte proliferation and induces various types of leukemias. Introduction of the SHP1 gene back into a leukemia cell line and a prostate cancer cell line demonstrated the tumor suppressor function of SHP1.

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Images

  • Western Blot analysis using SHP1 antibody (10R-8496) |

Availability: In stock

Price: $295.00
Size: 100 ul
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