SIRPA antibody (70R-10426)

Affinity purified rabbit polyclonal SIRPA antibody

Synonyms Polyclonal SIRPA antibody, Anti-SIRPA antibody, MYD-1 antibody, PTPNS1 antibody, BIT antibody, SIRPalpha antibody, SIRP-ALPHA-1 antibody, signal-regulatory protein alpha antibody, CD172A antibody, SHPS-1 antibody, MFR antibody, SIRP antibody, SIRPalpha2 antibody, SHPS1 antibody, P84 antibody
Cross Reactivity Human, Mouse, Rat, Bovine, Pig
Applications WB
Immunogen SIRPA antibody was raised in rabbit using the C terminal of SIRPA as the immunogen
Assay Information SIRPA Blocking Peptide, catalog no. 33R-7762, is also available for use as a blocking control in assays to test for specificity of this SIRPA antibody

Images

Western Blot analysis using SIRPA antibody (70R-10426)

SIRPA antibody (70R-10426) used at 0.2-1 ug/ml to detect target protein.

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance SIRPA is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein.

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Images

  • Western Blot analysis using SIRPA antibody (70R-10426) | SIRPA antibody (70R-10426) used at 0.2-1 ug/ml to detect target protein.

Availability: In stock

Price: $375.00
Size: 50 ug
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