SKP2 antibody (10R-2070)

Mouse monoclonal SKP2 antibody

Synonyms Monoclonal SKP2 antibody, Anti-SKP2 antibody, p45 antibody, SKP 2, SKP-2 antibody, SKP-2 antibody, SKP2, SKP-2, SKP 2 antibody, SKP 2 antibody, S phase kinase associated protein 2 antibody
Cross Reactivity Human
Applications ELISA, WB
Immunogen SKP2 antibody was raised in Mouse using a purified recombinant fragment of SKP2(aa1-130) expressed in E. coli as the immunogen.

Images

Western Blot analysis using SKP2 antibody (10R-2070)

Western Blot showing SKP2 antibody used against truncated Trx-SKP2 recombinant protein (1) and GST-SKP2 (aa1-130) recombinant protein (2).

Specifications

Host Mouse
Clone 6G9D10
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance SKP2 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs. SKP2 is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19).

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Images

  • Western Blot analysis using SKP2 antibody (10R-2070) | Western Blot showing SKP2 antibody used against truncated Trx-SKP2 recombinant protein (1) and GST-SKP2 (aa1-130) recombinant protein (2).

Availability: In stock

Price: $345.00
Size: 100 ul
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