SMAD4 antibody (10R-8554)

Mouse monoclonal SMAD4 antibody

Synonyms Monoclonal SMAD4 antibody, Anti-SMAD4 antibody, SMAD4 antibody, SMAD family member 4 antibody, BOS_22285 antibody, D18Wsu70e antibody, deleted in pancreatic carcinoma locus 4 antibody, deletion target in pancreatic carcinoma 4 antibody, deletion target in pancreatic carcinoma 4 homolog antibody, DPC4 antibody, EGK_09691 antibody, JIP antibody, madh4 antibody, MAD homolog 4 antibody, MAD homolog 4 (Drosophila) antibody, MAD (mothers against decapentaplegic Drosophila) homolog 4 antibody, MAD (mothers against decapentaplegic antibody, Drosophila) homolog 4 antibody, MAD antibody, mothers against decapentaplegic homolog 4 antibody, Med antibody, mothers against decapentaplegic antibody, Drosophila antibody, homolog of antibody, 4 antibody, mothers against decapentaplegic homolog 4 antibody, mothers against decapentaplegic-like 4 antibody, Mothers against decapentaplegic-like protein 4 antibody, mothers against DPP homolog 4 antibody, mothers against DPP-like 4 antibody, MYHRS antibody, SMA- and MAD-related protein 4 antibody, SMAD 4 antibody, SMAD4 protein antibody, SMAD antibody, mothers against DPP homolog 4 antibody
Cross Reactivity Human
Applications IP
Immunogen SMAD4 antibody was raised in Mouse using a recombinant human protein purified from E.coli(His-SMAD4) as the immunogen

Images

Western Blot analysis using Smad4 antibody (10R-8554)

Specifications

Host Mouse
Clone 31G4
Isotype IgG2a kappa
Method of Purification SMAD4 antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations IP: 2 ul

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Common SMAD (co-SMAD) is the coactivator and mediator of signal transduction by TGF-beta (transforming growth factor). Component of the heterotrimeric SMAD2/SMAD3-SMAD4 complex that forms in the nucleus and is required for the TGF-mediated signaling. Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription.

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Images

  • Western Blot analysis using Smad4 antibody (10R-8554) |

Availability: In stock

Price: $295.00
Size: 100 ul
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