SNAI2 antibody (10R-1900)
Mouse monoclonal SNAI2 antibody
|Synonyms||Monoclonal SNAI2 antibody, Anti-SNAI2 antibody, SNAI 2, SNAI-2 antibody, Zinc finger protein SNAI2 antibody, SNAI2, SNAI 2 antibody, SNAI-2|
|Immunogen||SNAI2 antibody was raised in Mouse using a purified recombinant fragment of human SNAI2 expressed in E. coli as the immunogen.|
Western Blot analysis using SNAI2 antibody (10R-1900)
Western Blot showing SNAI2 antibody used against SNAI2 (AA: 1-128)-hIgGFc transfected HEK293 cell lysate.
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||SNAI2 is a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporadic cases of neural tube defects.|
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