SNCA antibody (10R-8354)

Mouse monoclonal SNCA antibody

Synonyms Monoclonal SNCA antibody, Anti-SNCA antibody, alpha Synuclein antibody, NACP antibody, PARK1 antibody, Non A4 component of amyloid precursor antibody, Non-A-beta component of alzheimers disease amyloid antibody, precursor of antibody, PARK 1 antibody, PARK 4 antibody, PARK4 antibody, Parkinson disease familial 1 antibody, PD 1 antibody, PD1 antibody, Snca synuclein antibody, alpha (non A4 component of amyloid precursor) antibody, Synuclein alpha antibody, Synuclein antibody, alpha (non A4 component of amyloid precursor) antibody, alpha-Synuclein Delta-NAC antibody, Non-A beta component of AD amyloid antibody, Non-A4 component of amyloid precursor antibody, NACP antibody, alpha-synuclein antibody, alpha synuclein antibody, alpha-synuclein antibody, isoform NACP140 antibody, alphaSYN antibody, MGC105443 antibody, MGC110988 antibody, MGC127560 antibody, MGC64356 antibody, Non A beta component of AD amyloid antibody
Applications IF, WB

Images

Immunofluorescent staining using SNCA antibody (10R-8354)

Mixed neuron-glial cultures stained with alpha-synuclein (red) and chicken MAP2 (green)

Specifications

Host Mouse
Clone 3H9
Isotype IgG1
Form & Buffer Supplied in liquid form in Ascites fluid with 0.01 % NaN3

Usage & Assay Information

Usage Recommendations WB: 1:1000, IF: 1:500

General Information

Biological Significance Alpha-synuclein (amino acids 1-140), an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Specially, the non-Abeta component of amyloid plaques (NAC, amino acids 61-95) is a highly amyloidogenic peptide consisting of 35 amino acids which was first identified associated with senile plaques in the Alzheimer's disease brain.

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Images

  • Immunofluorescent staining using SNCA antibody (10R-8354) | Mixed neuron-glial cultures stained with alpha-synuclein (red) and chicken MAP2 (green)
  • Western Blot analysis using SNCA antibody (10R-8354) | Western blot of rat brain lysate showing specific immunolabeling of ~ 15k alpha synuclein protein

Availability: In stock

Price: $295.00
Size: 100 ul
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