SNCA protein (30R-1619)
Purified recombinant mouse SNCA protein
|Synonyms||Syn protein, alpha-Synuclein protein, NACP protein, Snca protein, Non-A4 component of amyloid precursor, Non-A beta component of AD amyloid protein|
Coomassie Blue stained SDS-PAGE of SNCA protein (30R-1619)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-140 amino acids: MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVTTVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGNIAA ATGFVKKDQM GKGEEGYPQE GILEDMPVDP GSEAYEMPSE EGYQDYEPEA|
|Purity||> 95% pure|
|Molecular Weight||14.4 kDa (140aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 7.5, containing 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Alpha-Synuclein, also known as SNCA, an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-Synuclein has been suggested to be implicated in the pathogenesis of Parkinson. Recombinant mouse alpha-Synuclein, was expressed in E. coli and purified by using conventional chromatography techniques|
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