SND1/P100 antibody (10R-1982)
Mouse monoclonal SND1/P100 antibody
|Synonyms||Monoclonal SND1/P100 antibody, Anti-SND1/P100 antibody, SND/P00 1, SND/P00 1 antibody, SND/P00-1 antibody, TudorSN antibody, SND1/P100, SND/P00-1, Staphylococcal nuclease and tudor domain containing 1 antibody|
|Immunogen||SND1/P100 antibody was raised in Mouse using a purified recombinant fragment of SND1 (aa361-485) expressed in E. coli as the immunogen.|
Western Blot analysis using SND1/P100 antibody (10R-1982)
Western Blot showing SND1/P100 antibody used against Hela (1), Jukat (2), HepG2 (3) SMMC-7721 (4) cell lysate.
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||SND1/P100 functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activatior of EBNA-2. It also interacts with EAV, NSP1,GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.|
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