SOD4 antibody (10R-8398)

Mouse monoclonal SOD4 antibody

Synonyms Monoclonal SOD4 antibody, Anti-SOD4 antibody, CCS antibody, copper chaperone for SOD antibody, anon-EST:Posey231 antibody, BOS_24810 antibody, CCD antibody, Ccsd antibody, CCS-PB antibody, CG-17753 antibody, CG17753 gene product from transcript CG17753-RB antibody, CG17753-PB antibody, copper chaperone of SOD antibody, Cu-chaperone for SOD antibody, DmCCS antibody, Dmel_CG17753 antibody, EGK_05959 antibody, SOD copper chaperone antibody, Superoxide dismutase 4 antibody
Cross Reactivity Human
Applications ELISA, IP
Immunogen SOD4 antibody was raised in Mouse using a recombinant human protein purified from E.coli as the immunogen

Images

Western Blot analysis using Superoxide Dismutase 4 antibody (10R-8398)

Specifications

Host Mouse
Clone 2A1
Isotype IgG1 kappa
Method of Purification SOD4 antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations IP: 1-2 ul

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance SOD(SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for SOD(CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc SODthrough direct insertion of the Cu cofactor.

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Images

  • Western Blot analysis using Superoxide Dismutase 4 antibody (10R-8398) |

Availability: In stock

Price: $295.00
Size: 100 ul
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