SPTLC1 antibody (70R-14314)

Affinity purified Rabbit polyclonal SPTLC1 antibody

Synonyms Polyclonal SPTLC1 antibody, Anti-SPTLC1 antibody, SPTLC-1 antibody, SPT1 antibody, LBC1 antibody, HSAN antibody, SPTLC 1, MGC14645 antibody, SPTLC1, SPTI antibody, HSN1 antibody, HSAN1 antibody, Serine Palmitoyltransferase Long Chain Base Subunit 1 antibody, SPTLC 1 antibody, LCB1 antibody, SPTLC-1
Applications IHC-P, WB
Immunogen SPTLC1 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence in the middle regionof human SPTLC1 as the immunogen

Images

Immunohistochemical staining using SPTLC1 antibody (70R-14314)

Immunohistochemistry of paraffin-embedded section of Human Mammary Cancer Tissue

Specifications

Host Rabbit
Isotype IgG
Method of Purification SPTLC1 antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. SPTLC1 is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in SPTLC1 gene were identified in patients with hereditary sensory neuropathy type 1.

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using SPTLC1 antibody (70R-14314)</font></div>     | Immunohistochemistry of paraffin-embedded section of Human Mammary Cancer Tissue
  • <div><font face=Calibri size=2>Western Blot analysis using SPTLC1 antibody (70R-14314)</font></div>     | Lane 1:SW620 Cell Lysate; Lane 2:S549 Cell Lysate; Lane 3:PANC Cell Lysate; Lane 4:U87 Cell Lysate

Availability: In stock

Price: $270.00
Size: 100 ug
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