Src antibody (10R-8485)

Mouse monoclonal Src antibody

Synonyms Monoclonal Src antibody, Anti-Src antibody, SRC antibody, v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) antibody, asv antibody, BOS_13447 antibody, CSK antibody, csrc antibody, c-Src antibody, c-src tyrosine kinase antibody, fc54g04 antibody, Fgr antibody, neuronal proto-oncogene tyrosine-protein kinase Src antibody, non-tyrosine protein kinase antibody, p60-src antibody, PP60C-SCR antibody, pp60c-src antibody, pp60v-src antibody, protein-tyrosine kinase antibody, proto-oncogene c-Src antibody, protooncogene SRC antibody, Rous sarcoma antibody, proto-oncogene tyrosine-protein kinase Src antibody, Rous sarcoma oncogene antibody, RP23-169M4.1 antibody, RP5-823N20.1 antibody, SDR antibody, src-1 antibody, SRC1 antibody, src oncogene antibody, Src protein antibody, tyrosine kinase pp60c-src antibody, tyrosine protein kinase c-src antibody, tyrosine protein kinase pp60-c-src antibody, tyrosine-protein kinase SRC-1 antibody, tyrosine-protein kinase Src42A-like antibody, v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog antibody, v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog antibody, v-src sarcoma viral oncogene antibody, xsrc antibody
Cross Reactivity Human, Mouse, Rat
Applications ELISA, WB
Immunogen Src antibody was raised in Mouse using a recombinant human protein purified from E.coli (His-src) as the immunogen

Images

Western Blot analysis using Src antibody (10R-8485)

Specifications

Host Mouse
Clone 5B8
Isotype IgG1 kappa
Method of Purification Src antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance The members of the Src-family kinases are Src, Lyn, Fyn, Yes, Hck, Lck, Fgr, Blk, and Yrk. Each of these have a common structure consisting of an unique domain at the N-terminal, followed by SH3, SH2 and tyrosine kinase domains. In immume cells, the Src-family kinases play roles as critical regulators of a large number of intracellular signaling pathways, including integrin signaling pathway. Integrins are major cellular receptor that mediate cell to cell and cell to substratum interactions. Src is expressed ubiquitously, however the expression level is higher in brain, osteoclasts, and platelets. Src plays a role in cell adhesion, cell morphology and motility, and bone resorption.

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Images

  • Western Blot analysis using Src antibody (10R-8485) |

Availability: In stock

Price: $295.00
Size: 100 ul
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