SRF antibody (10R-1760)

Mouse monoclonal SRF antibody

Synonyms Monoclonal SRF antibody, Anti-SRF antibody, SRF antibody, MCM1 antibody, MCM1 antibody, Anti SRF antibody, Serum response factor (c-fos serum response element-binding transcription factor) antibody, Serum response factor (c-fos serum response element-binding transcription factor) antibody
Specificity Human SRF
Cross Reactivity Human. Other species not studied
Applications Dot Blot, ICC
Immunogen SRF antibody was raised in mouse using recombinant Human Serum Response Factor (C-Fos Serum Response Element-Binding Transcription Factor) (Srf)

Images

Western blot analysis using SRF antibody (10R-1760)

Specifications

Host Mouse
Clone 173C1a
Isotype IgG1
Method of Purification SRF antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer SRF antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is amember of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs).

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Images

  • Western blot analysis using SRF antibody (10R-1760) |

Availability: In stock

Price: $190.00
Size: 50 ug
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