SSA 52 kDa protein (30-1291)

Purified recombinant SSA 52 kDa protein

Synonyms 52 kDa Ro protein, 52 kDa ribonucleoprotein autoantigen Ro protein, SS-A protein, RING finger protein 81 protein, TRIM21 protein, Ro(SS-A) protein, Sjoegren syndrome type A protein, SS A protein, SS-A protein, SSA
Species Human
Protein Type Recombinant
Applications ELISA, Immunoassays, WB

Specifications

Expression System E.coli
Form & Buffer Supplied in PBS buffer with 500 mM NaCl and 3M Urea

Usage & Assay Information

Usage Recommendations To be optimized by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage, aliquot and freeze at -20 deg C for long term storage

General Information

Biological Significance SSA 52 kDa is an intracellular antibody effector in the intracellular antibody-mediated proteolysis pathway. It binds to immunoglobulin G as well as immunoglobulin M on antibody marked non-enveloped virions which have infected the cell. Either by autoubiquitination or by ubiquitination of a cofactor, it is then responsible for directing the virions to the proteasome. SSA 52 kDa itself is not degraded in the proteasome unlike both the viral capsid and the bound antibody.

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Availability: In stock

Price: $1,195.00
Size: 1 mg
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