Stabilized Troponin I protein (Cardiac) (30-1003)

Purified recombinant Human Stabilized Troponin I protein (Cardiac)

Synonyms Cardiac-specific troponin I protein, cTnl protein, TnI protein, Troponin I protein
Species Human
Protein Type Recombinant

Specifications

Expression System E.coli
Form & Buffer Supplied in 500 mM NaCl, 5 mM sodium phosphate, 2 mM CaCl2, 0.5 mM EDTA, .025% Sodium Azide, pH 7.5
Concentration 10 - 50 ug/mL

Storage & Safety

Storage Store at -25 deg C or below. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.

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Availability: In stock

Price: $695.00
Size: 100 ug
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