SUPT4H1 antibody (10R-1444)

Mouse monoclonal SUPT4H1 antibody

Synonyms Monoclonal SUPT4H1 antibody, Anti-SUPT4H1 antibody, SUPT4H1, Suppressor of Ty 4 homolog 1 antibody, SPT4H antibody, SUPTH1-4, SUPTH1 4, SUPT4H antibody, SUPTH1 4 antibody, SUPTH1-4 antibody
Specificity Human SUPT4H1
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen SUPT4H1 antibody was raised in mouse using recombinant Human Suppressor Of Ty 4 Homolog 1 (S. Cerevisiae) (Supt4H1)

Images

Western Blot analysis of immunized recombinant protein using SUPT4H1 antibody (10R-1444)

Specifications

Host Mouse
Clone 3079C1a
Isotype IgG2b
Method of Purification SUPT4H1 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer SUPT4H1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance SUPT4H1 is a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II.

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Images

  • Western Blot analysis of immunized recombinant protein using SUPT4H1 antibody (10R-1444)

Availability: In stock

Price: $190.00
Size: 50 ug
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