Survivin protein (Calmodulin tag) (80R-1057)
Purified recombinant Human Survivin protein (Calmodulin tag)
|Synonyms||TIAP., BIRC 5 protein, Baculoviral IAP repeat containing protein 5 protein, Apoptosis Inhibitor 4 protein, BIRC5 protein, EPR 1 protein, API4 protein, SVV protein, Baculoviral IAP repeat containing 5 protein, Apoptosis inhibitor survivin protein, EPR-1 protein, Baculoviral IAP repeat-containing protein 5 isoform 1 API4 protein, Baculoviral IAP repeat-containing 5 protein, Apoptosis inhibitor4 protein, IAP4 protein, Survivin protein, Baculoviral IAP repeat-containing protein 5 isoform 1 protein|
Coomassie Blue stained SDS-PAGE of Survivin protein (Calmodulin tag) (80R-1057)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-142 amino acids: MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQVNYE EFVQMMTAKG SHMGAPTLPP AWQPFLKDHR ISTFKNWPFL EGCACTPERM AEAGFIHCPT ENEPDLAQCF FCFKELEGWE PDDDPIEEHK KHSSGCAFLS VKKQFEELTL GEFLKLDRER AKNKIAKETN NKKKEFEETA KKVRRAIEQL AAMD|
|Purity||> 90% pure|
|Molecular Weight||33 kDa (294 aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris, pH 7.5, containing 0.1M NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Survivin is a human gene that is part of the inhibitor of apoptosis family (IAP). The Survivin protein functions to inhibit caspase activation therefore leading to negative regulation of apoptosis or programmed cell death. Recombinant human Survivin fused to CaM-tag at N-terminus was expressed in E. coli and purified by conventional chromatography techniques.|
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