SYP antibody (10R-1894)

Mouse monoclonal SYP antibody

Synonyms Monoclonal SYP antibody, Anti-SYP antibody, Anti SYP antibody, p38 antibody, p38 antibody, Synaptophysin antibody, Synaptophysin antibody, SYP antibody
Cross Reactivity Hunam, Rat
Applications ELISA, WB
Immunogen SYP antibody was raised in Mouse using a purified recombinant fragment of SYP expressed in E. coli as the immunogen.

Images

Immunohistochemical staining using SYP antibody (10R-1894)

Immunohistochemical analysis of paraffin-embedded human Small Intestine, myenteric plexus tissues using anti-SYP antibody

Specifications

Host Mouse
Clone 7H12
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Synaptophysin is an integral membrane protein of small synaptic vesicles in brain and endocrine cells. Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore. Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases. Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex.

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Images

  • Immunohistochemical staining using SYP antibody (10R-1894) | Immunohistochemical analysis of paraffin-embedded human Small Intestine, myenteric plexus tissues using anti-SYP antibody
  • Western Blot analysis using SYP antibody (10R-1894) | Western Blot showing SYP antibody used against rat brain tissue lysate.

Availability: In stock

Price: $345.00
Size: 100 ul
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