TGF beta 1 antibody (10R-1836)
Mouse monoclonal TGF beta 1 antibody
|Synonyms||Monoclonal TGF beta 1 antibody, Anti-TGF beta 1 antibody, TGF beta-1 antibody, TGF beta 1 antibody, TGF beta-1, TGF beta 1, TGF beta 1, Transforming growth factor beta antibody|
|Immunogen||TGF beta 1 antibody was raised in Mouse using a purified recombinant fragment of TGFbeta1 expressed in E. coli as the immunogen.|
Western Blot analysis using TGF beta 1 antibody (10R-1836)
Western Blot showing TGF beta1 antibody used against truncated TGF beta1 recombinant protein.
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||TGF beta is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. In mammals, three isoforms of TGFbeta, that is, beta1, beta2,and beta3 are known. TGF beta is one of numerous inhibitory factors produced by cancer cells that regulate antitumor immunity. TGF beta1 takes part in the local response in the course of primary lung cancer and TGFbeta1 is thought to be implicated in breast cancer progression. TGFbeta1 also plays a critical role in the downregulation of microglial responses minimizing brain inflammation and thus avoiding exacerbation of brain damage.|
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