TGF beta 1 antibody (10R-T106a)

Mouse monoclonal TGF beta 1 antibody

Synonyms Monoclonal TGF beta 1 antibody, Anti-TGF beta 1 antibody, Cartilage-inducing factor antibody, Differentiation inhibiting factor antibody, TGF-1b antibody, TGF beta 1 antibody, TGF beta 1, TGF beta-1, TGF beta-1 antibody, TGF beta 1, Transforming Growth Factor-beta1 antibody, TGFB1 antibody, TGF beta-1 antibody
Specificity Human TGF-beta1
Cross Reactivity To be determined by end-user
Applications ELISA, Inhibition, WB
Immunogen TGF beta 1 antibody was raised in mouse using highly pure recombinant human TGF-beta1 as the immunogen.

Specifications

Host Mouse
Clone M66
Isotype IgG1 kappa
Molecular Weight 25 kDa (predicted detection band MW)
Form & Buffer Lyophilized from PBS.

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance The three mammalian isoforms of TGF beta, TGF beta1, beta2, beta3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes including embryogenesis, tissue remodeling and wound healing. They are secreted predominantly as latent complexes which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF beta isoform from a latent complex involves proteolytic processing of the complex and /or induction of conformational changes by proteins such as thrombospondin-1. TGF beta1 is the most abundant isoform secreted by almost every cell type. It was originally identified for its ability to induce phenotypic transformation of fibroblasts and recently it has been implicated in the formation of skin tumors.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Availability: In stock

Price: $225.00
Size: 500 ug
OR
Shipping
View Our Distributors