THAP1 protein (His tag) (80R-2257)
Purified recombinant Human THAP1 Protein (His tag)
|Synonyms||THAP 1 protein, THAP-1, THAP1, THAP 1, THAP-1 protein, DYT6 protein, THAP domain-containing protein 1 protein|
Coomassie Blue stained SDS-PAGE of THAP1 protein (His tag) (80R-2257)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||MGSSHHHHHH SSGLVPRGSH MGSHMVQSCS AYGCKNRYDK DKPVSFHKFP LTRPSLCKEW EAAVRRKNFK PTKYSSICSE HFTPDCFKRE CNNKLLKENA VPTIFLCTEP HDKKEDLLEP QEQLPPPPLP PPVSQVDAAI GLLMPPLQTP VNLSVFCDHN YTVEDTMHQR KRIHQLEQQV EKLRKKLKTA QQRCRRQERQ LEKLKEVVHF QKEKDDVSER GYVILPNDYF EIVEVPA|
|Purity||> 85% pure|
|Molecular Weight||27.5 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer, pH 8.0 containing 2M Urea, 10% glycerol, 1mM DTT, 0.2M NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||THAP1 contains a THAP domain, a conserved DNA-binding domain. This protein colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies, and functions as a proapoptotic factor that links PAWR to PML nuclear bodies.|
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