TIFF3 protein (30R-AT079)

Purified recombinant Human TIFF3 protein

Synonyms TIFF-3 protein, TIFF 3, Intestinal trefoil factor protein, TIFF-3, Trefoil Factor 3 protein, ITF protein, TIFF-3 protein, TFI protein, TIFF 3 protein, TIFF3
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of TIFF3 protein corresponding to amino acids EEYVGLSANQ CAVPAKDRVD CGYPHVTPKE CNNRGCCFDS RIPGVPWCFK PLQEAECTF.
Expression System E.coli
Purity > 98% pure
Molecular Weight 13.2 kDa
Form & Buffer Supplied as a lyophilized powder.

Usage & Assay Information

Bioactivity Determined by its ability to chemoattract human MCF-7 cells using a concentration range of 1.0-10.0 ug/ml.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are secreted in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF-3 is expressed by goblet cells and in the uterus, and has also been shown to express in certain cancers, including colorectal, hepatocellular, and in biliary tumors. TFF3 may be useful as a molecular marker for certain types of cancer, but its role, if any, in tumorigenesis is unknown. TFF3 also promotes airway epithelial cell migration and differentiation.

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Availability: In stock

Price: $225.00
Size: 20 ug
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