TLR2 antibody (N-terminal) (70R-14928)

Rabbit polyclonal TLR2 antibody (N-terminal)

Synonyms Polyclonal TLR2 antibody, Anti-TLR2 antibody, Toll like receptor 2 antibody, TLR2, TLR 2, TLR-2, TLR 2 antibody, TLR-2 antibody, TLR2 antibody N Terminal, TLR2 antibody N Terminal Region, CD282 antibody, TIL4 antibody
Cross Reactivity Human: 100%, Dog: 85%
Applications IHC, WB
Immunogen TLR2 antibody was raised in Rabbit using asynthetic peptide directed towards the N terminal of human TLR2 as the immunogen
Assay Information TLR2 Blocking Peptide, catalog no. 33R-11063, is also available for use as a blocking control in assays to test for specificity of this TLR2 antibody

Images

Immunohistochemical staining using TLR2 antibody (N-terminal)(70R-14928)

Immunohistochemical analysis ofhuman macrophange cells using TLR2 antibody at 1:200 dilution

Specifications

Host Rabbit
Method of Purification TLR2 antibody was purified by affinity chromatography
Molecular Weight 90 kDa
Form & Buffer Supplied in lyophilized form, to reconstitute Add 50 ul of distilled water. Final anti-TLR2 antibody concentration is 1 mg/ml in PBS buffer.

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term store at -20 deg C. avoid Freeze/Thaw cycles

General Information

Biological Significance The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. CD14+ monocytes expressed the highest level of TLR2 followed by CD15+ granulocytes, and CD19+ B-cells, CD3+ T-cells, and CD56+ NK cells did not express TLR2. The expression of TLR2 on different cell types are regulated by different immune response modifiers. For example, LPS, GM-CSF, IL-1, and IL-10 up regulates TLR2 whereas IL-4, IFN-gamma, and TNF down regulate TLR2 expression in monocytes.

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Images

  • Immunohistochemical staining using TLR2 antibody (N-terminal)(70R-14928) | Immunohistochemical analysis ofhuman macrophange cells using TLR2 antibody at 1:200 dilution
  • Western Blot analysis using TLR2 antibody (N-terminal)(70R-14928) | Western Blot using TLR2 antibody at 1 ug/ml

Availability: In stock

Price: $345.00
Size: 50 ug
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