TNFa protein (30R-2148)

Purified recombinant Mouse TNFa Protein

Synonyms Tumor necrosis factor protein, Cachectin protein, TNFalpha protein, TNFSF2 protein, Tnfsf1a protein, DIF protein, TNF-alpha protein
Species Mouse
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of TNFa protein (30R-2148)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues MLRSSSQNSS DKPVAHVVAN HQVEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLVY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VNLLSAVKSP CPKDTPEGAE LKPWYEPIYL GGVFQLEKGD QLSAEVNLPK YLDFAESGQV YFGVIAL
Expression System E.coli
Purity > 95% pure
Molecular Weight 17.4 kDa
Form & Buffer Supplied in liquid form in Phosphate buffered saline, pH 7.4.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance TNFa is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

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Images

  • Coomassie Blue stained SDS-PAGE of TNFa protein (30R-2148) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $275.00
Size: 100 ug
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