TNFRSF1A antibody (70R-10434)

Affinity purified rabbit polyclonal TNFRSF1A antibody

Synonyms Polyclonal TNFRSF1A antibody, Anti-TNFRSF1A antibody, TNF-R-I antibody, p55 antibody, TNFR1 antibody, member 1A antibody, tumor necrosis factor receptor superfamily, TNFR60 antibody, TBP1 antibody, TNF-R antibody, TNFAR antibody, TNFRSFA-1, TNF-R55 antibody, MGC19588 antibody, TNFRSF1A, FPF antibody, CD120a antibody, TNFRSFA 1 antibody, TNFRSFA 1, p55-R antibody, TNFR55 antibody, p60 antibody, TNFRSFA-1 antibody
Cross Reactivity Human, Mouse, Rat
Applications IHC, WB
Immunogen TNFRSF1A antibody was raised in rabbit using the N terminal of TNFRSF1A as the immunogen
Assay Information TNFRSF1A Blocking Peptide, catalog no. 33R-6046, is also available for use as a blocking control in assays to test for specificity of this TNFRSF1A antibody

Images

Western blot analysis using TNFRSF1A antibody (70R-10434)

Recommended TNFRSF1A Antibody Titration: 0.2-1 ug/ml

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance TNFRSF1A is the receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. TNFRSF1A contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

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Images

  • Western blot analysis using TNFRSF1A antibody (70R-10434) | Recommended TNFRSF1A Antibody Titration: 0.2-1 ug/ml
  • Immunofluorescent staining using TNFRSF1A antibody (70R-10434) | Human Lymphocytes

Availability: In stock

Price: $345.00
Size: 50 ug
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