TNFSF10 antibody (70R-10455)

Affinity purified rabbit polyclonal TNFSF10 antibody

Synonyms Polyclonal TNFSF10 antibody, Anti-TNFSF10 antibody, TNFSF-10 antibody, ligand superfamily, TNFSF 10 antibody, TNFSF-10, TNFSF10, member 10 antibody, tumor necrosis factor, TNFSF 10, TRAIL antibody, Apo2L antibody, Apo-2L antibody
Cross Reactivity Human, Dog, Pig
Applications WB
Immunogen TNFSF10 antibody was raised in rabbit using the N terminal of TNFSF10 as the immunogen
Assay Information TNFSF10 Blocking Peptide, catalog no. 33R-1684, is also available for use as a blocking control in assays to test for specificity of this TNFSF10 antibody

Images

Western Blot analysis using TNFSF10 antibody (70R-10455)

TNFSF10 antibody (70R-10455) used at 0.2-1 ug/ml to detect target protein.

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance TNFSF10 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis.

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Images

  • Western Blot analysis using TNFSF10 antibody (70R-10455) | TNFSF10 antibody (70R-10455) used at 0.2-1 ug/ml to detect target protein.

Availability: In stock

Price: $345.00
Size: 50 ug
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