Tnk1 antibody (10R-2156)
Mouse monoclonal Tnk1 antibody
|Synonyms||Monoclonal Tnk1 antibody, Anti-Tnk1 antibody, Tnk 1 antibody, Tnk-1, Tnk1, Tnk-1 antibody, NRPTK antibody, Tyrosine kinase non receptor 1 antibody, Tnk 1|
|Immunogen||Tnk1 antibody was raised in Mouse using a purified recombinant fragment of Tnk1(aa451-560) expressed in E. coli as the immunogen.|
Western Blot analysis using Tnk1 antibody (10R-2156)
Western Blot showing TNK1 antibody used against truncated TNK1-His recombinant protein (1).
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Tnk1 is a nonreceptor tyrosine kinase. These kinases, like members of the SRC and JAK families, mediate intracellular signaling downstream of receptor activation. Tnk1 is a ubiquitously expressed 47-kDa protein with autotyrosine kinase activity that is developmentally regulated during embryogenesis. Tnk1 is also upregulated following IL3 withdrawal from factor-dependent murine NSF/N1. H7 cells that undergo apoptosis, suggesting a role in growth inhibition.|
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