TP53 antibody (Ser392) (70R-15039)

Rabbit polyclonal TP53 antibody (Ser392)

Synonyms Polyclonal TP53 antibody, Anti-TP53 antibody, TP-53 antibody, TP 53 antibody, TP53, Tumor protein p53 antibody, p53 antibody, Phosphoprotein p53 antibody, Cellular tumor antigen p53 antibody
Applications WB

Images

Western Blot analysis using TP53 antibody (Ser392) (70R-15039)

Western blot of rat brain nuclear fraction lysate showing specific immunolabeling of ~53kp53 phosphorylated at Ser392 (Control)

Specifications

Host Rabbit
Method of Purification TP53 antibody was purified by affinity chromatography
Form & Buffer Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000

General Information

Biological Significance p53 (aka TP53) is a transcription factor whose protein levels and post-translational modification state alter in response to cellular stress (such as DNA damage, hypoxia, spindle damage). Activation of p53 begins through a number of mechanisms including phosphorylation by ATM, ATR, Chk1 and MAPKs. MDM2 is a ubiquitn ligase that binds p53 and targets p53 for proteasomal degradation.

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Images

  • Western Blot analysis using TP53 antibody (Ser392) (70R-15039) | Western blot of rat brain nuclear fraction lysate showing specific immunolabeling of ~53kp53 phosphorylated at Ser392 (Control)

Availability: In stock

Price: $335.00
Size: 100 ul
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