tPA protein (30C-CP1109)

Purified Recombinant tPA protein (Human)

Synonyms Tissue Plasminogen Activator protein, t-PA protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Expression System CHO cells
Purity > 95% pure
Form & Buffer Lyophilized from 100mM PBS, with 3.5 mg/ml L-arginine, and 0.001% polysorbate Tween 80. Reconstitute with 1 ml distilled water.

Usage & Assay Information

Bioactivity Specific Activity is at least 300,000 IU/mg.Activity is determined by Plasminogen activating capacity of bound t-PA (via immobilized antibody).

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Tissue plasminogen activator (abbreviated TPA or PLAT) is a protein involved in the breakdown of blood clots. It is a serine protease found on endothelial cells, the cells that line the blood vessels. As an enzyme, it catalyzes the conversion of plasminogen to plasmin, the major enzyme responsible for clot breakdown. Because it works on the clotting system, tPA is used in clinical medicine to treat only embolic or thrombotic stroke. Use is contraindicated in hemorrhagic stroke and head trauma.

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Availability: In stock

Price: $495.00
Size: 1 mg
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