TRAF1 antibody (70R-10512)

Affinity purified rabbit polyclonal TRAF1 antibody

Synonyms Polyclonal TRAF1 antibody, Anti-TRAF1 antibody, TRAF 1, TRAF-1 antibody, TNF receptor-associated factor 1 antibody, TRAF 1 antibody, TRAF-1, TRAF1, MGC:10353 antibody, EBI6 antibody
Cross Reactivity Human, Mouse, Rat, Bovine, Dog, Zebrafish
Applications WB
Immunogen TRAF1 antibody was raised in rabbit using the middle region of TRAF1 as the immunogen
Assay Information TRAF1 Blocking Peptide, catalog no. 33R-1850, is also available for use as a blocking control in assays to test for specificity of this TRAF1 antibody

Images

Western Blot analysis using TRAF1 antibody (70R-10512)

Western Blot showing TRAF1 antibody used at a concentration of 1-2 ug/ml to detect its target protein.

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance This protein is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors.

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Images

  • Western Blot analysis using TRAF1 antibody (70R-10512) | Western Blot showing TRAF1 antibody used at a concentration of 1-2 ug/ml to detect its target protein.

Availability: In stock

Price: $345.00
Size: 50 ug
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