TRAIL Receptor 1 protein (30R-AS050)

Purified recombinant Human TRAIL Receptor 1 protein

Synonyms DR4 protein, TRAIL R1 antibody, soluble TRAIL Receptor-1 protein, TNFRSF10A protein, TRAIL Receptor-1 protein, TRAIL R1 antibody, Apo2 protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of TRAIL Receptor 1 protein corresponding to amino acids MSGTGAAAAT PSKVWGSSAG RIEPRGGGRG ALPTSMGQHG PSARARAGRA PGPRPAREAS PRLRVHKTFK FVVVGVLLQV VPSSAATIKL HDQSIGTQQW EHSPLGELCP PGSHRSERPG ACNRCTEGVG YTNASQQLFA CLPCTACKSD EEERSPCTTT RNTACQCKPG TFRNDNSAEM CRKCSTGCPR GMVKVKDCTP WSDIECVHKE SGNGHN.
Expression System E.coli
Purity > 98% pure
Molecular Weight 22.7 kDa
Form & Buffer Supplied as a lyophilized powder.

Usage & Assay Information

Bioactivity Determined by its inhibitory effect of IL-8 production in human PBMC by human sTRAIL/Apo2L. 95% inhibition (100 ng/ml of s TRAIL/Apo2L) was reached using a concentration of 100 ng/ml of sTRAIL Receptor-1.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance TRAIL Receptor-1/DR4 and TRAIL Receptor-2/DR5 belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic "death domain, " which can activate the cell's apoptotic machinery. These receptors are activated by binding to either membrane anchored or soluble TRAIL/Apo2L.

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Availability: In stock

Price: $225.00
Size: 50 ug
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