Transferrin antibody (20R-2963)

Rabbit polyclonal Transferrin antibody

Synonyms Polyclonal Transferrin antibody, Anti-Transferrin antibody, TF antibody, transferrin antibody, beta-1 metal-binding globulin antibody, Beta-1-metal-binding globulin antibody, BmTf antibody, FBgn0003685 antibody, lactotransferrin antibody, liver regeneration-related protein LRRG03 antibody, ltf antibody, PRO1400 antibody, pro1557 antibody, PRO2086 antibody, serotransferrin antibody, siderophilin antibody, Tfn antibody, TFQTL1 antibody, tissue factor antibody, transcription elongation regulator 1 antibody, trefoil antibody, Trf antibody, tufted antibody
Cross Reactivity Human
Applications IP, WB
Immunogen Transferrin antibody was raised in Rabbit using a protein purified from Human plasma as the immunogen

Images

Western Blot analysis using Transferrin antibody (20R-2963)

Specifications

Host Rabbit
Isotype IgG
Method of Purification Transferrin antibody was purified by Protein A affinity chromatography
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:5000, IP: 3 ul

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance When a Transferrin protein loaded with iron encounters a transferrin receptor (TfR) on the surface of a cell it binds to it and is consequently transported into the cell by endosomes. ATP-dependent proton pumps then force H+ ions into the endosomes reducing the pH to 5.5, thus promoting iron release and conformational change of the receptor enabling apo-transferrin to remain bound. The binding characteristics of the apo-Tf?TfR complex are such that the apo-Tf is released only once the complex reaches the cell surface.

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Images

  • Western Blot analysis using Transferrin antibody (20R-2963) |

Availability: In stock

Price: $295.00
Size: 100 ul
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