Transthyretin antibody (10R-8510)

Mouse monoclonal Transthyretin antibody

Synonyms Monoclonal Transthyretin antibody, Anti-Transthyretin antibody, TTR antibody, transthyretin antibody, ATTR antibody, BOS_22125 antibody, carpal tunnel syndrome 1 antibody, CH1073-351M12.2 antibody, CTS antibody, CTS1 antibody, D17860 antibody, EGK_09613 antibody, FBgn0003871 antibody, HsT2651 antibody, Lr1 antibody, PALB antibody, prealbumin antibody, prealbumin antibody, amyloidosis type I antibody, TBPA antibody, tetrapter antibody, thyroxine-binding prealbumin antibody, transthyretin (prealbumin antibody, amyloidosis type 1) antibody, transthyretin (prealbumin antibody, amyloidosis type I) antibody, xTTR antibody
Cross Reactivity Human
Applications ELISA, IP, WB
Immunogen Transthyretin antibody was raised in Mouse using a protein purified from Human plasma as the immunogen
Assay Information This antibody can be used as the detection antibodypaired with Transthyretin antibody (10R-8457) as the capture antibodyin sandwich immunoassays such as ELISA.

Images

Western Blot analysis using Transthyretin antibody (10R-8510)

Specifications

Host Mouse
Clone 9G6
Isotype IgG1 kappa
Method of Purification Transthyretin antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:2000, IP: 1 ul

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Transthyretin (TTR, 55 kDa homotetramer) is a thyroid hormone-binding protein that transports thyroxine (T4) from the bloodstream to the brain. TTR was originally called prealbumin because it ran faster than albumin on electrophoresis gels. TTR is produced in the liver and circulates in the bloodstream, where it binds retinol and thyroxine. TTR is suggested that plays an essential role in brain function. The protein consists of around 130 amino acids, which assemble as a homotetramer that contains an internal channel in which T4 is bound. Within this complex, T4 appears to be transported across the blood-brain barrier, where, in the choroid plexus, the hormone stimulates further synthesis of transthyretin. The protein then diffuses back into the bloodstream, where it binds T4 for transport back to the brain.

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Transthyretin antibody

Mouse monoclonal Transthyretin antibody

Images

  • Western Blot analysis using Transthyretin antibody (10R-8510) |

Availability: In stock

Price: $295.00
Size: 100 ul
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