Transthyretin protein (30R-3017)

Purified recombinant Transthyretin protein

Synonyms TTR protein, Prealbumin protein, Amyloid polyneuropathy protein, Amyloidosis I protein, ATTR protein, Dysprealbuminemic euthyroidal hyperthyroxinemia protein, Dystransthyretinemic hyperthyroxinemia protein, HsT2651 protein, PALB protein, Prealbumin amyloidosis type I protein, Senile systemic amyloidosis protein, TBPA protein, Transthyretin protein, TTR protein, TTR protein protein
Species Human
Protein Type Recombinant
Applications WB

Images

Western Blot analysis using Transthyretin protein (30R-3017)

Specifications

Expression System E.coli
Purity > 90% pure
Molecular Weight 40.5 kDa
Form & Buffer Supplied in lyophilized form from 20mM HEPES, pH7.0
Concentration 1mg/ml

Storage & Safety

Storage Store at -80 deg C. Avoid frequent freeze/thaw cycles

General Information

Biological Significance Transthyretin, generally called prealbumin, is a plasma protein that plays an important role in physiology such as a transporter of hormone thyroxine and retinal-binding protein. After produced primarily in the liver, TTR is excreted into the plasma. TTR represents a disproportionate fraction (25%) of CSF protein, prompting the suggestion that it is either selectively transported across the blood-CSF barrier or synthesized de novo within the central nervous system. Transthyretin is a constituent found to the neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. It has been reported that more than 40 different mutations in the TTR gene associated with amyloid deposition.

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Images

  • Western Blot analysis using Transthyretin protein (30R-3017) |

Availability: In stock

Price: $195.00
Size: 500 ug
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