TRKA antibody (10R-1909)

Mouse monoclonal TRKA antibody

Synonyms Monoclonal TrkA antibody, Anti-TrkA antibody, TrkA antibody, Trk A antibody, Trk-A antibody, Anti TrkA antibody, Trk A antibody, Trk-A antibody
Cross Reactivity Human
Applications ELISA, IF, WB
Immunogen TRKA antibody was raised in Mouse using purified recombinant extracellular fragment of human TrkA(aa33-423) fused with hIgGFc tag expressed in HEK293 cell line as the immunogen.

Images

Immunofluorescent staining using Western Blot analysis using TRKA antibody (10R-1909) (TRKA antibody)

Confocal immunofluorescence analysis of PC-12 cells using TrkA antibody (green), showing membrane and cytoplasmic localization. Blue: DRAQ5 fluorescent DNA dye.

Specifications

Host Mouse
Clone 6B2
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IF: 1:200-1:1000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance High affinity nerve growth factor receptor also known as neurotrophic tyrosine kinase receptor type 1 or TRK1-transforming tyrosine kinase protein or Trk-A is a protein that in humans is encoded by the NTRK1 gene. This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself (autophosphorylation) and members of the MAPK pathway.

References
Add a Paper

Sylvia E. Pereza, Bin Hea, Nadeem Muhammada, Kwang-Jin Oha, Margaret Fahnestockb, Milos D. Ikonomovicc, Elliott J. Mufson

Cholinotrophic basal forebrain system alterations in 3xTg-AD transgenic mice

Neurobiology of Disease

Volume: 41 Issue: 2 Page: 338-352 DOI: 10.1016/j.nbd.2010.10.002

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Images

  • Immunofluorescent staining using Western Blot analysis using TRKA antibody (10R-1909) (TRKA antibody) | Confocal immunofluorescence analysis of PC-12 cells using TrkA antibody (green), showing membrane and cytoplasmic localization. Blue: DRAQ5 fluorescent DNA dye.
  • Western Blot analysis using TRKA antibody (10R-1909) | Western Blot showing TrkA antibody used against extracellular domain of human TrkA (aa33-423).

Availability: In stock

Price: $345.00
Size: 100 ul
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